PIWIL1 anticorps (N-Term)

N° du produit ABIN6991434

Cet anticorps anti-PIWIL1 est un anticorps Lapin Polyclonal détectant PIWIL1 dans WB, ELISA, IF et IHC (p). Adapté pour Humain, Souris et Rat.

Aperçu rapide pour PIWIL1 anticorps (N-Term) (ABIN6991434)

Antigène: PIWIL1 (Piwi-Like 1 (PIWIL1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PIWIL1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-PIWIL1 anticorps

Épitope: AA 60-110, N-Term

Purification: PIWI-L1 Antibody is affinity chromatography purified via peptide column.

Immunogène: PIWI-L1 antibody was raised against an 18 amino acid synthetic peptide near the amino terminus of human PIWI-L1. The immunogen is located within amino acids 60 - 110 of PIWI-L1.

Isotype: IgG

Information d'application

Indications d'application: PIWI-L1 antibody can be used for detection of PIWI-L1 by Western blot at 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 10 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in rat samples and Immunofluorescence in rat samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PIWI-L1 Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: PIWI-L1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur PIWIL1

Antigène: PIWIL1 (Piwi-Like 1 (PIWIL1))

Autre désignation: PIWI-L1

Sujet: PIWI-L1 Antibody: PIWI-L1 is a member of the PIWI subfamily of Argonaute proteins, evolutionarily conserved proteins containing both PAZ and Piwi motifs that are crucial for the biogenesis and function of small non-coding RNAs and play important roles in stem cell self-renewal, RNA silencing, and translational regulation in diverse organisms. PIWI-L1 is thought to play a role as an intrinsic regulator of the self-renewal capacity of germline and hematopoietic stem cells as removing PIWI-L1 protein from single germline stem cells significantly decreases the rate of their division. Recent studies have shown that overexpression of PIWI-L1 (as well as other PIWI-like proteins) are potential biomarkers for colon and other cancers.

Poids moléculaire: Predicted: 85, 90 kDa

Observed: 95 kDa

ID gène: 9271

UniProt: Q96J94